Summary: The claustrum (CLA) is a conspicuous subcortical structure interconnected with cortical and subcortical regions.Its regional anatomy and cell-type-specific connections in the mouse remain hp 15-da0008ca not fully determined.Using multimodal reference datasets, we confirmed the delineation of the mouse CLA as a single group of neurons embed
The stable environment of subterranean realms is characterized by constant darkness, temperature and humidity, and scarcity of resources.This led to similar adaptations in different lineages of animals, such as the reduction of eyes and pigmentation.It is common textbook knowledge that blindness in cave insects is compensated for by transformations
Secretory cargo that cannot fold properly in the ER are selectively targeted for removal by a well-studied ER-associated degradation pathway, or ERAD.In contrast, very little is known about post-ER quality control mechanisms for damaged or misfolded integral membrane proteins.Here we describe a quality control function of the Rsp5-ART ubiquitin lig